产品货号：
Z27640
中文名称：
STIM1抗体
英文名称：
Anti-STIM1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STIM1 Antibody |
| 指标别名 | D11S4896E;GOK;STIM1;stromal interaction molecule 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | STIM1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human STIM1(45-74aa AAEFCRIDKPLCHSEDEKLSFEAVRNIHKL),identical to the related mouse and rat sequences. |
| 实际分子量 | 97KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene.STIM1 has a single transmembranedomain,and is localized to the endoplasmic reticulum,and to a lesser extent to the plasma membrane.This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs).It is one of several genes located in the imprinted gene domain of 11p15.5,an important tumor-suppressor gene region.Alterations in this region have been associated with the Beckwith-Wiedemann syndrome,Wilms tumor,rhabdomyosarcoma,adrenocrotical carcinoma,and lung,ovarian,and breast cancer.This gene may play a role in malignancies and disease that involve this region,as well as early hematopoiesis,by mediating attachment to stromal cells.Mutations in this gene are associated with fatal classic Kaposi sarcoma,immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts,ectodermal dysplasia and tubular aggregate myopathy.This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1),with the 3' end of this gene situated 1.6kb from the 5' end of the RRM1 gene.Alternative splicing of this gene results in multiple transcript variants. |
| Uniprot ID | Q13586 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | stromal interaction molecule 1 |
| 蛋白名全称 | Stromal interaction molecule 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：STIM1抗体，STIM1多抗，Anti-STIM1 Antibody